Force field parameters made by DFF can be used for simulation directly. Internal simulation engines can be used for energy minimization and molecular dynamics simulations. In addition, DFF works with popular external simulation engines such as GROMACS, LAMMPS, TOWHEE, CHARMM, AMBER, and DISCOVER. Force field parameters made by DFF can be exported to those simulation engines. GROMACS and LAMMPS can be run directly from DFF.